Newsletter Issue 19: BBC Horizon Special part 2	July 2012
BBC Horizon: Sugar is a major factor in ageing, and Anti-glycation is a key pathway. This is the second special Newsletter in response to BBC's Horizon's fascinating programme "The Truth About Looking Younger". If you missed part 1, you can click the link to read it now. Featured Anti-Glycation Ingredient: Ameliox   It is no surprise that our partner Mibelle Biochemistry offers key active ingredients that directly fit the 3 main aspects covered by Horizon! This is the second of 3 special Newsletters in response to the programme.
Glycation: how the sugar we eat is ageing us! BBC Horizon covered the very interesting and depressing fact that eating a lot of sugar not only makes us put on weight, it can make us look older. Why? Glycation. Glycation is where sugar becomes attached to collagen and in doing so makes the collagen stiffer and more brittle, leading to a loss of elasticity. A study showed how individuals with lower blood glucose levels typically looked up to 2 years younger than those with higher blood glucose levels. Glycation is a slow naturally-occurring process which affects the structure and the activity of proteins. As well as increased sugar intake in our diets, oxidative stress factors and notably lipid peroxidation accelerate the glycation process. Anti-glycation was identified as of key importance to Anti-ageing. We offer Ameliox, an ingredient proven to offer anti-glycation efficacy and much more! Ameliox Ameliox is a liposomal complex of carnosine, an antioxidant and anti- glycation substance, with 2 powerful oil-soluble antioxidants (silymarin and tocopherol). Ameliox is able to inhibit lipid peroxidation and so, prevents and slows down the glycation process. In a clinical study, Ameliox was shown to: * Increase skin firmness, smoothness and hydration * Reduce the depth of wrinkles by 27 % in the crow’s feet area and by 24 % on the forehead after 1 month of treatment. INCI: Lecithin (and) Carnosine (and) Tocopherol (and) Silybum Marianum Fruit Extract (and) Glycerin (and) Alcohol* (and) Aqua / Water * An alcohol-free version (Ameliox oA) is also available. >> Visit the Ameliox product page
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Other Anti-Glycation Ingredients Inoveol PHLO from Induchem Inoveol PHLO (Phloridzinyl Glucoside) is a natural enhancer of melanogenesis with skin matrix protection. Its primary use is in tanning products and to offer skin radiance. Inoveol PHLO has anti-glycation properties and protects the extracellular matrix by MMP-9 inhibition. It soothes the skin by inhibition of interleukin-8 release. >> Visit the product page Phyto-SIRT from Barnet Phyto-SIRT is an optimum complex of Mexican Bamboo as a resource of Resveratrol, Boldine from the Chilean Boldo Tree as a powerful antioxidant, Aminoguanadine HCl and decarboxy carnosine HCl to prevent glycation. >> Visit the product page
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For further information about any of the products mentioned in this newsletter, please email us or contact your usual ProTec representative.
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